Saturday, September 5, 2009

Genomic information of Mycobacteroum tyberculosis , Salmonella typhimurium and Treponema pallidum :

Genomic information of Mycobacteroum tyberculosis , Salmonella typhimurium and Treponema pallidum :

Organisms: Mycobacterium tuberculosis F 11
Mycobacterium tuberculosis is causative agent of Tuberculosis ( TB) . It is a aerobic bacteria and it infects lungs of human.

Genome information:

Total number DNA: 1
Topology : Circular
Size of DNA molecule : 4424435 bp
Number of Genes: 3950
Hypothetical genes: 92
tRNA : 45
r RNA : 3
Number of A : 760565 bp
Number of T :760652 bp
Number of G :1448726 bp
Number of C :1454492 bp
Number of A+T : 1521217 bp
Number of G+C : 2903218 bp

Organism :
Salmonella typhimurium LT2 SGSC1412
Salmonella typhimurium is a gram negative bacterium. It may cause gastroenteritis.

Genome information:

Total number DNA: 2 ( Plasmid DNA & Chromosome DNA)

Plasmid DNA:

Molecule Name : plasmid pSLT Salmonella typhimurium LT2 SGSC1412
Topology : Circular
Size of DNA Molecule : 93939 bp
Number of Genes: 162
tRNA : 0
r RNA : 0
Number of A : 22312 bp
Number of T : 21719 bp
Number of G : 25838 bp
Number of C : 24070 bp
Number of A+T : 44031 bp
Number of G+C : 49908 bp

Chromosome DNA:

Molecule Name : chromosome Salmonella typhimurium LT2 SGSC1412
Topology: Circular
Size of DNA molecule : 4857432 bp
Number of Genes: 5695
tRNA : 85
r RNA : 19
Number of A: 1160904 bp
Number of T :1159904 bp
Number of G :1268216 bp
Number of C :1268408 bp
Number of A+T: 2320808 bp
Number of G+C :2536624 bp

Organism: Treponema pallidum Nichols

Treponema pallidum is a spirochaete bacterium. It cause Syphilis ( Sexually Transmitted Disease).

Genome information:

Total number DNA: 1
Topology : Circular
Size of DNA molecule : 1138012 bp
Number of Genes: 1039
Hypothetical genes: 282
tRNA : 45
r RNA : 6
Number of A :267895 bp
Number of T :269498 bp
Number of G :302333 bp
Number of C :298219 bp
Number of A+T: 537393 bp
Number of G+C :600552 bp

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Microbial Diseases of Blood

Microbial Diseases of Blood:

Blood is a unique body fluid that contains RBC , WBC and Thrompocytes. . Blood transports nutrients and oxygen to cells. WBC of blood consist neutrophil, basophil, eosinophil, lymphocytes and Monocytes.
Like other site of human body (eg: skin, nervous system etc) blood also infected by microorganisms. Microbial disease of blood are as follows…

Bacterial Disease:

1 childbed fever (Puerperal fever) ---- Streptococcus pyogenes
2 Anthrax (Woolsorter's disease) ---- Bacillus anthracis
3 Plague ---------------------------- Yersinia pestis
4 Tularemia ------------- Francisella tularensis
5 Epidemic relapsing fever --------- Borrelia recurrentis
6 Lyme disease ------------- Borrelia burgdorferi

Viral Disease:

1) Yellow Fever ------ Yellow Fever Virus
2) Dengue Fever (dengue hemorrhagic fever) –----- Dengue Virus.
3) Infectious mononucleosis - ---- Epstein-Barr Virus
4) Fifth Disease (Erythema infectiosum) ---- Parovirus strain B19.
5) AIDS (acquired immunodeficiency syndrome) --- HIV type 1 (or) HIV type 2.

Rickettsial Disease:

1) Epidemic Typhus --------- Rickettsia prowazekii
2) Endemic Typhus ---------- Rickettsia typhi
3) Scrub Typhus ----------- Rickettsia tsutsugamushi
4) Rocky Mountain Spotted Fever ---- Rickettsia rickettsii
5) Rickettsialbox --------- Rickettsia akari
6) Trench Fever ---- Rochalimaea Quintana

Protozoan Disease :

1) Malaria -------- Plasmodium vivax , P. ovale , P. malariae
2) Toxoplasmosis ---- Toxoplasma gondii
3) Babesiosis ----- Babesia microti